A research team investigated the association of body mass index (BMI), smoking, and alcohol intake with the risk of multiple myeloma (MM) mortality.
The analysis included 805,309 participants contributing 10,221,623 person-years of accumulated follow-up across Asia Cohort Consortium cohorts. Hazard ratios (HRs) and 95% confidence intervals (95% CIs) for the association between BMI, smoking and alcohol at baseline and the risk of MM mortality were assessed.
A statistically significant dose-dependent association was observed between BMI categories and the risk of MM mortality and the association was more apparent in women than in men. No significant associations between smoking or alcohol consumption and risk of MM mortality were observed.
This study showed that excess body mass is associated with an increased risk of MM mortality among Asian populations. The results do not support an association between smoking or alcohol consumption and the risk of MM mortality in Asian populations.
Source: Association of BMI, smoking and alcohol with multiple myeloma mortality in Asians: a pooled analysis of more than 800,000 participants in the Asia Cohort Consortium. Ugai T. Cancer Epidemiol Biomarkers Prev. 2019 Aug 9.