Moderate alcohol consumption is generally associated with reduced risk of type 2 diabetes. However, this beneficial effects of alcohol intake remains controversial due to inconsistent results across studies.
An analysis was performed using data from the Ansung-Ansan cohort study. The participants were categorised into four groups-based on the baseline (one-point measure; non-drinking, < 5 g/day, >/= 5, < 30 g/day, and >/= 30 g/day) and follow-up (consumption pattern; never-drinking, light, moderate, and heavy drinking) measurement. At baseline, >/= 30 g/day alcohol consumption increased the risk of incident diabetes (HR: 1.42; 95% CI, 1.10-1.85), but >/= 5, < 30 g/day alcohol consumption had no effects on the incident diabetes. When using the alcohol consumption pattern, a heavy-drinking pattern increased the risk of incident diabetes (HR = 1.32), but the light and moderate consumption pattern was associated with a reduced risk of type 2 diabetes (HR: 0.66 and HR: 0.74 respectively). At the end point of follow-up, the insulinogenic index (IGI), but not the insulin sensitivity index (ISI), differed among the groups.
Alcohol consumption pattern had a J-shaped association with the incident type 2 diabetes in Korean men. The IGI showed an inverted J-shaped association according to alcohol drinking pattern, but the ISI was not a J-shape.
Source: Association between alcohol consumption pattern and the incidence risk of type 2 diabetes in Korean men: a 12-years follow-up studyLee DY; Yoo MG; Kim HJ; Jang HB; Kim JH; Lee HJ; Park SI Scientific Reports Vol 7, Art No 7322, 2017, 7pp.