Page last updated: Tuesday, August 24, 2010
Alcohol and type 2 diabetes -  A review

A review sought to describe a) the association between alcohol consumption and the risk of type 2 diabetes (T2D) and b) the impact of alcohol on the glycemic control with and without anti-diabetic drugs.
For the first part of the review the researchers selected meta-analyses, review articles and observational studies more recent than year 1990 including at least 1000 participants. For the second part of they included all articles more recent than year 1990. Most observational studies find a J-shaped association between alcohol intake and incidence of T2D. Interestingly, drinking pattern plays a role, i.e. binge drinking increases the risk of T2D. Opposing information exists about the influence of beverage type. In T2D the acute effects on plasma glucose, insulin, fatty acids and triglyceride vary, in part depending on concomitant intake of food. Acute alcohol intake does not induce hypoglycemia in diet treated T2D, but increases the risk of hypoglycemia in sulphonylurea treated patients. In most studies, long-term alcohol use is associated with improved glycemic control in T2D.
The researchers conclude that moderate alcohol consumption reduces the incidence of T2D, however, binge drinking seems to increase the incidence. Acute intake of alcohol does not increase risk of hypoglycemia in diet treated subjects with T2D, only when sulphonylurea is co-administered. Long-term moderate alcohol use seems to be associated with improved glycemic control in T2D probably due to improved insulin sensitivity.

Source: Alcohol and type 2 diabetes. A review A. Pietraszek, S. Gregersen, K. Hermansen. Nutrition, Metabolism and Cardiovascular Diseases, Volume 20, Issue 5, Pages 366-375
no website link
All text and images © 2003 Alcohol In Moderation.