Type 2 diabetes is common in industrial countries and is a major
cause of cardiovascular disease and all-cause mortality. The study
by Wei M et al and published by Diabetes Care, vol 23, No1, included 8,633 men with fasting plasma glucose measurements from
at least two medical examinations. Alcohol intake was classified
into 5 groups: non -drinkers and 4 quartiles (Qs) of drinkers
according to the amount of alcohol intake. Type 2 diabetes was
diagnosed by 1997 American Diabetes Association criteria.
Results: There was a U-shaped association between alcohol intake and diabetes
with the lowest incidence of diabetes at Q2. Men in Q3 and Q4
had a 2.2 - 2.4 fold risk of developing diabetes, while non-drinkers
and men in Q1 had 1.8 - fold and 1.4- fold higher risk of diabetes,
respectively. After adjustments for age, fasting plasma glucose,
smoking, BMI, blood pressure, serum triglyceride concentration,
cardiorespiratory fitness, HDL cholesterol, waist circumference
and parental diabetes these associations persisted.
An elevated risk of developing type 2 diabetes was observed in
non-drinkers and men with high alcohol intakes, when compared
with men who reported moderate alcohol intake. The risk of developing
type 2 diabetes in men with a high alcohol intake may be reduced
if they drink less.
Source: Wei M; Gibbons LW; Mitchell TL; Kampert JB; Blair SN, " Alcohol
intake and incidence of type 2 diabetes in men", Diabetes Care, vol 23, No1, pp18-22