Researchers conducted a meta-analysis of crosssectional studies assessing the relationship between alcohol consumption and the risk of erectile dysfunction (ED).
Medical databases were searched in order to identify relevant studies. 24 studies (154,295 patients) were included. A random effects metaanalysis was performed to estimate a combined study-specific odds ratio (OR).
The meta-analysis results indicated that light to moderate alcohol consumption (<21 drinks/ week) was correlated with a decreased risk of erectile dysfunction (OR = 0.71; 95% CI: 0.59-0.86; P = 0.000). However, irregular (ever vs. never) and high alcohol consumption (>21 drinks/week) had influence on the prevalence of ED (regular: OR = 0.87; 95% CI: 0.75-1.07; P = 0.062; high: OR = 0.99; 95% CI: 0.80-1.22; P = 0.893). In a doseresponse meta-analysis, a non-linear relationship was observed between alcohol consumption and risk of ED (P for non-linearity = 0.0000). In conclusion, moderate intake of alcohol exhibited a beneficial effect on the risk of ED, whereas regular and high consumption had no significant effect.
Source: Alcohol intake and risk of erectile dysfunction: a dose-response meta-analysis of observational studies. Wang XM, Bai YJ, Yang YB, Li JH, Tang Y, Han P. Int J Impot Res. 2018 Sep 19.