This study investigated the relation between alcohol consumption and the risk of cardiovascular disease (CVD) among 10,530 hypertensive women from the EPIC-NL cohort.
Researchers assessed alcohol consumption using validated food-frequency questionnaire and participants were followed for occurrence of CVD.
During 9.4 years follow-up, 58- coronary heart disease (CHD) events and 254 strokes, (165 of which were ishcemic) were documented.
An inverse association (Ptrend=0.009) between alcohol consumption and risk of CHD was observed with a multivariate-adjusted hazard ratio of 0.72 (95% confidence interval: 0.52-1.01) for those consuming 70-139.9g alcohol/week compared to lifetime abstainers. Of different beverages, only red wine consumption was associated with a reduced risk of CHD. A U-shaped relation (P=0.08) was observed for total stroke with a hazard ratio of 0.65 (0.44 -0.95) for consuming 5-69.9g alcohol/week compared with lifetime abstainers. Similar results were observed for ischemic stroke with a hazard ratio of 0.56 (0.35-0.89) for consuming of 5-69.9 g alcohol/week.
The authors conclude that moderate alcohol consumption is associated with a reduced risk of CHD among hypertensive women. Light alcohol consumption tended to be related to a lower risk of stroke. Current guidelines for alcohol consumption in the general population also apply to hypertensive women.
Source: Alcohol consumption and risk of cardiovascular disease among hypertensive women Bos, Sarah et al. European Journal of Cardiovascular Prevention & Rehabilitation: February 2010 - Volume 17 - Issue 1 - pp 119-126