Moderate alcohol consumption is related to a reduction of mortality. However, this phenomenon is not well established in the elderly, especially in the presence of chronic heart failure (CHF). The aim of this study was to verify the effect of moderate alcohol consumption on 12-year mortality in elderly community-dwelling with and without CHF.
The study cohort included 1332 community-dwelling subjects aged 65 and older from 5 regions of Italy.
Mortality after 12-year follow-up in elderly subjects (≥65 years old) with and without CHF was studied. Moderate alcohol consumption was considered ≤250 ml/day (drinkers).
In the absence of CHF (n=947), mortality was 42.2% in drinkers vs. 53.7% in non-drinker elderly subjects. In contrast, in the presence of CHF (n=117), mortality was 86.5% in drinkers vs. 69.7% in non-drinker elderly subjects. Accordingly, Cox regression analysis shows that a moderate alcohol consumption is protective of mortality in the absence (HR=0.79; CI 95% 0.66–0.95; p<0.01) but it is predictive of mortality in the presence of CHF (HR=1.29; CI 95% 1.05–1.97; p<0.05).
The authors conclude that their data demonstrates that moderate alcohol consumption is associated with an increased long-term mortality risk in the elderly in the presence of Chronic Heart Failure, but is protective in it’s absence.
Source: Moderate alcohol consumption predicts long-term mortality in elderly subjects with chronic heart failure. G. Gargiulo, G. Testa, F. Cacciatore, F. Mazzella, G. Galizia, D. Della-Morte, A. Langellotto, G. Pirozzi, G. Ferro, N. Ferrara, F. Rengo, Pasquale Abete The journal of nutrition, health & aging February 2013