A study investigated the incidence, prevalence, hospitalization rates and survival for alcoholic liver disease (ALD) in Denmark 2006–2011.
Using nationwide healthcare registries all Danish residents with a hospital diagnosis of ALD were identified and standardized incidence, prevalence, and hospitalization rates in 2006–2011, age- and birth cohort-specific incidence for the 1930–1974 birth cohorts, and 1- and 5-year survival were computed.
In 2006–2011, the overall standardized ALD incidence decreased from 343 to 311 per 1,000,000 population per year. ALD incidence increased among women aged 65 years or older, but decreased in younger persons and men. Persons born in 1950–1959 had higher age-specific incidence than earlier and later birth cohorts. The prevalence (0.2% of the Danish adult population) and hospitalization rate were constant. The 1- and 5-year survival were 70 and 43%, respectively. Men had poorer survival than women, and patients with alcoholic cirrhosis or alcoholic hepatitis had poorer survival than patients with alcoholic steatosis.
In Denmark, persons born in 1950–1959 have had the highest age-specific incidence. The overall ALD incidence has been decreasing (along with per capita consumption). Despite increases in affordability during the study period, Denmark did not experience the increase in ALD seen, for example, in the UK.
Source: Epidemiology of Alcoholic Liver Disease in Denmark 2006–2011: A Population-Based Study. Thomas Deleuran , Hendrik Vilstrup , Ulrik Becker, Peter Jepsen. Alcohol and Alcoholism, first published online: 13 February 2015.